ANSC 5980

Animals in Biomedical Research

Course Description

Course information provided by the Courses of Study 2022-2023.

This course introduces features and applications of various animal models and related cutting-edge tools for biomedical research on human health and diseases. Examples will be given on appropriate animal models for studying human diseases related to diabetes, bone, infection, brain, eye, and nutritional deficiencies. Model species include food-producing animals, recreational/companion animals, and laboratory animals. Lectures cover basic biology, common uses of animals in biomedical research, and unique applications of selected species for target human disease. Comparative physiology between model species and humans, advantages and limitations of given models, regulations of biomedical uses of animals, and combined applications of animal models with omics, machine learning, and big data are also discussed.

When Offered Spring.

Prerequisites/Corequisites Prerequisite: two semesters of college-level biology; BIOAP 1100 or equivalent introductory physiology course.

• To be able to describe importance, contribution, and potential of animal models in biomedical research.
• To be able to elaborate physiological bases and molecular mechanisms of animals in modeling human health and disease.
• To be able to select appropriate animal models for studying pathophysiology, diagnosis, and treatment of common human diseases.
• To be able to find out limitations, alternatives, and regulations of animal models in biomedical research.
• To be able to apply new concepts and novel technology for biomedical farming and for developing rewarding careers integrating animal science and biomedical research.
• To be able to critically evaluate appropriateness of selected animal models for a given human disease and to propose for innovation and improvements.
• To be able to develop unique animal models, new medical materials, and novel tools.

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