PLPPM 4250

DNA Targeting: Applications, Reagents, and Impact

Course Description

Course information provided by the Courses of Study 2018-2019.

Recent advances in our capacity to direct molecules to specific DNA sequences in vitro and in living cells give us an unprecedented ability to probe and modify the genetic material. Through primary literature, this course considers applications of DNA targeting, ranging from systems biology to genome editing; reagents, including zinc finger proteins, TAL effectors, the CRISPR/Cas9 complex and others; and impact, reaching basic science, agriculture, and medicine. Regulatory, ethical, intellectual property, and public perception considerations are also discussed.

When Offered Spring.

Prerequisites/Corequisites Recommended prerequisite: BIOMG 2800 and BIOMG 2801 or equivalent; BIOMG 3300, BIOMG 3310 with BIOMG 3320, BIOMG 3330, or BIOMG 3350;  BIOMG 4000.

Distribution Category (OPHLS-AG)

• Possess detailed knowledge and in depth understanding of major topics in the field of DNA targeting
• Critically evaluate research articles in the field of DNA targeting.
• Find, access, and manage relevant publications.

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